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Rekombinanter CD4 Antikörper (Extracellular Domain)

Name: Rekombinanter CD4 Antikörper (Extracellular Domain)
Brand: antibodies-online
SKU: ABIN5668249
Availability: InStock

Der Maus Monoklonal anti-CD4 Antikörper (Klon MT310) (ABIN5668249) detektiert spezifisch CD4 in FACS, IP, IF, IHC (p), Inh und BP. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Rhesusaffen und Cynomolgus.

Immunohistochemical staining of guinea pig skin tissue using anti-CD4 antibody MT310 Anti-CD4 staining of formaldehyde fixed paraffin embedded guinea pig skin tissue, at 40x magnification. (Rekombinanter CD4 Antikörper (Extracellular Domain))

IHC

1 image

Produktnummer ABIN5668249

-20% for 20 Years of ABO

499,20 €

~~624,00 €~~

Sparen Sie 124,80 € (-20 %)

Zzgl. Versandkosten 20,00 € und MwSt

200 μg

Lieferung nach: Deutschland

Lieferung in 4 bis 8 Werktagen

Kurzübersicht für Rekombinanter CD4 Antikörper (Extracellular Domain) (ABIN5668249)

Target

Alle CD4 Antikörper anzeigen

CD4

Antikörpertyp

Recombinant Antibody

Reaktivität

Human, Rhesusaffen, Cynomolgus

Wirt

Maus

Klonalität

Monoklonal

Konjugat

Dieser CD4 Antikörper ist unkonjugiert

Applikation

Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Inhibition (Inh), Blocking Peptide (BP)

Klon

MT310

Discover our top product CD4 Primärantikörper

Bindungsspezifität
26

18

16

16

16

16

13

13

12

11

10

9

7

7

4

4

4

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Extracellular Domain

Verwendungszweck

Anti-CD4 [MT310], Mouse IgG1, kappa

Spezifität

This antibody is specific for the CD4 extracellular domain D1 (binding the HIV-1 gp120-binding site).
Application Notes original Clone: This antibody strongly inhibits HIV-1 gp120-binding to CD4, which blocks HIV infectivity of CD4⁺ T lymphocytes, as well as the binding of MHCII, which results in the block of T-cell activation (possibly leading to anergy induction) (Qin et al., 2001, PMID: n/a). Additionally, antibody binding to CD4 leads to GM-CSF, TNF-α and IL-10 induction. (TNF-α induction only occurs after 20hours.)

Kreuzreaktivität

Cynomolgus, Rhesusaffen

Aufreinigung

Protein A affinity purified

Isotyp

IgG1, kappa
anti-CD4 (CD4) (AA 385-457) antibody
CD4 Reaktivität: Human FACS, WB, IHC (fro), IHC (p), IF (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated

anti-CD4 (CD4) antibody
CD4 Reaktivität: Human, Maus, Ratte, Affe, Huhn, Hund, Kaninchen, Rind (Kuh), Schaf, Meerschweinchen, Ziege, Schwein, Pferd, Avian, Esel, Hamster WB, IHC (fro), IHC (p) Wirt: Ziege Polyclonal unconjugated

anti-CD4 (CD4) (AA 231-330) antibody
CD4 Reaktivität: Maus FACS, WB, IHC (fro), IHC (p), IF (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated

anti-CD4 (CD4) (N-Term) antibody
CD4 Reaktivität: Human FACS, WB, MS Wirt: Maus Monoclonal MEM-241 unconjugated

anti-CD4 (CD4) antibody
CD4 Reaktivität: Human, Maus, Ratte IHC Wirt: Maus Monoclonal unconjugated

anti-CD4 (CD4) (AA 26-200) antibody
CD4 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated

anti-CD4 (CD4) antibody (PE)
CD4 Reaktivität: Ratte FACS Wirt: Maus Monoclonal OX-35 PE

anti-CD4 (CD4) antibody
CD4 Reaktivität: Maus FACS, IP, IHC (fro), ICC, Func Wirt: Ratte Monoclonal GK1-5 unconjugated

anti-CD4 (CD4) (N-Term) antibody (FITC)
CD4 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-241 FITC

anti-CD4 (CD4) (N-Term) antibody (PE)
CD4 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-241 PE

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Kommentare

OriginalSpeciesName: Mouse
OriginalFormat: IgG1

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1 mg/mL

Buffer

PBS with 0.02 % Proclin 300.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Target

CD4

Andere Bezeichnung

CD4

Hintergrund

Leu3/T3, T-cell differentiation antigen, Ly-4, L3T4, T-cell surface antigen T4/Leu-3

UniProt

P01730

Pathways

T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events