Rekombinanter CD19 Antikörper

Produktnummer ABIN5668223

Dieser Kaninchen Chimeric Antikörper detektiert spezifisch CD19 in FACS, IHC, IP, IF, SPR und BP. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter CD19 Antikörper (ABIN5668223)

Target: CD19 (CD19 Molecule (CD19))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser CD19 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Surface Plasmon Resonance (SPR), Blocking Peptide (BP)

Klon: HD37

Produktdetails anti-CD19 Antikörper

Verwendungszweck: Anti-CD19 [HD37], Rabbit IgG, kappa

Spezifität:

This antibody is specific for human CD19, a 95 kDa protein expressed in the B-lymphocyte lineage.

Application Notes original Clone: This antibody binds to CD19 and is able to inhibit B-cell activation (Pezutto 1987). This antibody was measured to have a K_D of 4.1 ± 0.3 nM against human CD19 and did not compete with clone FMC63 (available as Ab00613) (Sakemura et al., 2023, PMID: 37879074).

Produktmerkmale: This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Aufreinigung: Protein A affinity purified

Immunogen: Cells from a hairy cell leukemia patient.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

OriginalSpeciesName: Mouse

OriginalFormat: IgG1

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu CD19

Target: CD19 (CD19 Molecule (CD19))

Andere Bezeichnung: CD19

Hintergrund: Leu12, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, Differentiation antigen CD19 T-cell surface antigen Leu-12, CD19

UniProt: P15391

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung