Rekombinanter CD19 Antikörper
Kurzübersicht für Rekombinanter CD19 Antikörper (ABIN5668223)
Target
Alle CD19 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-CD19 [HD37], Rabbit IgG, kappa
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Spezifität
- This antibody is specific for human CD19, a 95 kDa protein expressed in the B-lymphocyte lineage.
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Produktmerkmale
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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Aufreinigung
- Protein A affinity purified
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Immunogen
- Cells from a hairy cell leukemia patient.
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Isotyp
- IgG kappa
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Applikationshinweise
- This antibody binds to CD19 and is able to inhibit B-cell activation (Pezutto 1987). This antibody was measured to have a KD of 4.1 ± 0.3 nM against human CD19 and did not compete with clone FMC63 (available as Ab00613) (Sakemura et al., 2023, PMID: 37879074).
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Kommentare
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This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CD19 (CD19 Molecule (CD19))
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Andere Bezeichnung
- CD19
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Hintergrund
- Leu12, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, Differentiation antigen CD19 T-cell surface antigen Leu-12, CD19
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UniProt
- P15391
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Pathways
- Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
Target
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