Rekombinanter CD33 (Gemtuzumab Biosimilar) Antikörper
Kurzübersicht für Rekombinanter CD33 (Gemtuzumab Biosimilar) Antikörper (ABIN5668210)
Target
Antikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-CD33 [hP67.6 (Gemtuzumab)], Human IgG4, kappa
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Spezifität
- Recognises human CD33.
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Produktmerkmale
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Original Species of Ab: Human
Original Format of Ab: IgG4
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Aufreinigung
- Protein A affinity purified
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Reinheit
- > 98 % as determined by SDS-PAGE
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Endotoxin-Niveau
- Endotoxin is < 1.0 EU/mg as determined by the LAL method
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Immunogen
- Gemtuzumab was generated by huminization of the murine P67.6 clone, raised against CD33-transfected FMY9S5 cells of human origin. CD33 is a transmembrane receptor expressed on predominantly on cells of the myeloid lineage, but it can also be found on some lymphoid cells.
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Isotyp
- IgG4 kappa
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anti-CD33 (Gemtuzumab Biosimilar) antibody
Research Grade Reaktivität: Human FACS Wirt: Humanized Monoclonal unconjugated Recombinant Antibody
anti-CD33 (Gemtuzumab Biosimilar) antibodyReaktivität: Human FACS, IF Wirt: Kaninchen Chimeric HP67-6 unconjugated Recombinant Antibody
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Applikationshinweise
- A human IgG4 variant conjugated to derivative of the cytotoxic drug calicheamicin gamma 1, N-acetylcalicheamicin dimethyl hydrazide, has been used as a therapeutic against acute myeloid leukemia. This antibody may also be used in flow cytometry and immunofluorescence.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CD33 (Gemtuzumab Biosimilar)
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Substanzklasse
- Biosimilar
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Hintergrund
- Siglec-3
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UniProt
- P20138
Target
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