Rekombinanter CD32/CD16 Antikörper

Produktnummer ABIN5668181

Dieser Kaninchen Chimeric Antikörper detektiert spezifisch CD32/CD16 in FACS, IP, IHC, IF und BR. Es zeigt Reaktivität gegenüber Proben von Maus.

Kurzübersicht für Rekombinanter CD32/CD16 Antikörper (ABIN5668181)

Target: CD32/CD16

Antikörpertyp: Recombinant Antibody

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser CD32/CD16 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunofluorescence (IF), Blocking Reagent (BR)

Klon: 2-4G2

Produktdetails anti-CD32/CD16 Antikörper

Verwendungszweck: Anti-CD16/CD32 [2.4G2], Rabbit IgG, kappa

Spezifität: This antibody binds to an epitope on the extracellular domains of the mouse FcγIII and FcγII, thereby inhibiting their ability to bind antibodies via their Fc region. receptors. Also binding the FcγI receptor (CD64) via its Fc domain.

Produktmerkmale:

Original Species of Ab: Rat

Original Format of Ab: IgG2b

Aufreinigung: Protein A affinity purified

Immunogen: Mouse BALB/c Macrophage J774 Cell Line.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: This antibody binds murine Fc Receptors CD16/CD32 and inhibits binding of antibodies to these. It can therefore be used as an Fc-blocking reagent, to reduce non-specific staining of cells by antibodies binding via their Fc-region. A similar effect can be achieved using the Fc Silent range of antibodies made by Absolute Antibody that prevent these interactions at the level of the Fc receptor binding site, which has been mutated to lack affinity for the Fc receptors.

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2b format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu CD32/CD16

Target: CD32/CD16

Andere Bezeichnung: CD16/CD32

Hintergrund: Fcγ III/II Receptor, Low affinity immunoglobulin gamma Fc region receptor III, IgG Fc receptor III, Fc-gamma RIII, FcRIII, CD16, Low affinity immunoglobulin gamma Fc region receptor II, Fc gamma receptor IIB, Fc-gamma RII, Fc-gamma-RIIB, FcRII IgG Fc rec

UniProt: P08508, P08101