Rekombinanter VEGF Antikörper
Kurzübersicht für Rekombinanter VEGF Antikörper (ABIN5668149)
Target
Alle VEGF Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-VEGF [A.4.6.1], Mouse IgG1, kappa
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Spezifität
- Binds native and reduced human VEGF (isoform 165), with a Kd of 0.8 nm determined for the original clone.
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Kreuzreaktivität
- Ratte
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Produktmerkmale
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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Aufreinigung
- Protein A affinity purified
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Immunogen
- Recombinant human VEGF.
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Isotyp
- IgG1 kappa
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Applikationshinweise
- This is the parental antibody clone to the humanized, therapeutic antibody Bevacizumab (marketed as Avastin) binding to VEGF. VEGF is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. It induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- VEGF (Vascular Endothelial Growth Factor (VEGF))
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Andere Bezeichnung
- VEGF
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Hintergrund
- VEGF-A, Vascular Endothelial Growth Factor, VEGFA, Vascular Permeability Factor, VPF
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UniProt
- P15692
Target
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