Rekombinanter V alpha TCR Antikörper

Produktnummer ABIN5668026

Dieser Kaninchen Chimeric Antikörper detektiert spezifisch V alpha TCR in ELISA, FACS und WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter V alpha TCR Antikörper (ABIN5668026)

Target: V alpha TCR

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS), Western Blotting (WB)

Klon: 34

Produktdetails

Verwendungszweck: Anti-Vα TCR [34], Rabbit IgG, kappa

Spezifität: This antibody binds to the T-cell receptor alpha chains.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: scFv

Aufreinigung: Protein A affinity purified

Immunogen: Purified recombinant soluble TCR from the T-cell hybridoma 85.33, corresponding to V alpha 11

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: The antibody binds specifically to the recombinant and native variable domain of the α chain which comprises the T-cell receptor (TCR). The TCR is a disulfide-linked heterodimeric protein expressed on the surface of T-cells in complex with CD3 and ζ-chain molecules. The receptor functions in the recognition of MHC molecule and the subsequent activation of T-cells. The monoclonal antibody 34 recognises Vα regions of TCRs expressed in the 85.33 arthritogenic T-cell hybridoma and can be used to analyse TCR V gene expression and for immunotherapy in T cell mediated autoimmunity.

Kommentare:

This full-length, chimeric rabbit antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Antigendetails

Target: V alpha TCR

Hintergrund: TCR variable alpha chain, T-cell receptor variable alpha chain

UniProt: P01848