ITGA3 Antikörper (PE)
Kurzübersicht für ITGA3 Antikörper (PE) (ABIN5665751)
Target
Alle ITGA3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-Hu CD49c PE
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Kreuzreaktivität (Details)
- Human
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Produktmerkmale
- The mouse monoclonal antibody ASC-1 recognizes an extracellular epitope of CD49c (integrin alpha 3), a transmembrane glycoprotein composed of disulfide linked 125 kDa and 30 kDa chains, and expressed on adherent cell lines and to a lesser extent on T and B cells and monocytes.
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Aufreinigung
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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Immunogen
- Human SSC-9 cell line (squamous cell carcinoma)
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Do not freeze,Protect from prolonged exposure to light
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- ITGA3 (Integrin, alpha 3 (ITGA3))
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Andere Bezeichnung
- CD49c
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Hintergrund
- Integrin subunit alpha 3,CD49c / Integrin alpha 3 is a type I transmembrane glycoprotein proteolytically cleaved into two disulfide linked chains. It noncovalently associates with CD29 (integrin beta 1) to form the VLA-3 complex, an adhesion receptor for extracellular matrix components (fibronectin, laminin 1, laminin 5, entactin, and collagen). It is expressed on adherent cells, mainly on fibroblasts, epithelial cells and endothelial cells.,ITGA3, VLA-3 alpha, FRP-2, FRP2, GAPB3
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Gen-ID
- 3675
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UniProt
- P26006
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Pathways
- CXCR4-mediated Signaling Events, Integrin Complex
Target
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