GRHL2 Antikörper (AA 111-210)

Produktnummer ABIN566411

Der Maus Polyklonal Anti-GRHL2-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, GRHL2 in Proben von Human zu detektieren. Es sind 4+ Publikationen verfügbar.

Kurzübersicht für GRHL2 Antikörper (AA 111-210) (ABIN566411)

Target: GRHL2 (Grainyhead-Like 2 (GRHL2))

Reaktivität: Human

Wirt: Maus

Klonalität: Polyklonal

Konjugat: Dieser GRHL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-GRHL2 Antikörper

Bindungsspezifität: AA 111-210

Verwendungszweck: Mouse polyclonal antibody raised against a partial recombinant GRHL2.

Sequenz: ENRVQVLKTV PVNLSLNQDH LENSKREQYS ISFPESSAII PVSGITVVKA EDFTPVFMAP PVHYPRGDGE EQRVVIFEQT QYDVPSLATH SAYLKDDQRS

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: GRHL2 (NP_079191, 111 a.a. ~ 210 a.a) partial recombinant protein with GST tag.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 50 % glycerol

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-GRHL2 Antikörper (ABIN566411)

Werner, Frey, Riethdorf, Schulze, Alawi, Kling, Vafaizadeh, Sauter, Terracciano, Schumacher, Pantel, Assmann: "Dual roles of the transcription factor grainyhead-like 2 (GRHL2) in breast cancer." in: The Journal of biological chemistry, Vol. 288, Issue 32, pp. 22993-3008, (2013) (PubMed).

Chen, Xiao Liu, Oh, Shin, Kim, Jiang, Park, Kang: "Grainyhead-like 2 (GRHL2) inhibits keratinocyte differentiation through epigenetic mechanism." in: Cell death & disease, Vol. 3, pp. e450, (2012) (PubMed).

Chen, Dong, Shin, Kim, Oh, Park, Kang: "Grainyhead-like 2 enhances the human telomerase reverse transcriptase gene expression by inhibiting DNA methylation at the 5'-CpG island in normal human keratinocytes." in: The Journal of biological chemistry, Vol. 285, Issue 52, pp. 40852-63, (2010) (PubMed).

Kang, Chen, Kim, Kang, Park: "Regulation of the hTERT promoter activity by MSH2, the hnRNPs K and D, and GRHL2 in human oral squamous cell carcinoma cells." in: Oncogene, Vol. 28, Issue 4, pp. 565-74, (2009) (PubMed).

Details zu GRHL2

Target: GRHL2 (Grainyhead-Like 2 (GRHL2))

Andere Bezeichnung: GRHL2

Hintergrund: Full Gene Name: grainyhead-like 2 (Drosophila)
Synonyms: BOM,DFNA28,FLJ11172,FLJ13782,MGC149294,MGC149295,TFCP2L3

Gen-ID: 79977

NCBI Accession: NM_024915

Pathways: Tube Formation