MAPKBP1 Antikörper (AA 1-100)

Produktnummer ABIN5664104

Der Kaninchen Polyklonal Anti-MAPKBP1-Antikörper wurde für WB validiert. Er ist geeignet, MAPKBP1 in Proben von Human zu detektieren.

Kurzübersicht für MAPKBP1 Antikörper (AA 1-100) (ABIN5664104)

Target: MAPKBP1 (Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPKBP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MAPKBP1 Antikörper

Bindungsspezifität: AA 1-100

Sequenz: MAVEGSTITS RIKNLLRSPS IKLRRSKAGN RREDLSSKVT LEKVLGITVS GGRGLACDPR SGLVAYPAGC VVVLFNPRKH KQHHILNSSR KTITALAFSP

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAPKBP1 (NP_001122080.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MAPKBP1

Target: MAPKBP1 (Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1))

Andere Bezeichnung: MAPKBP1

Hintergrund: This gene encodes a scaffold protein that regulates the JNK (c-Jun N-terminal kinase) and NOD2 (nucleotide-binding oligomerization domain-containing protein 2) signaling pathways. The encoded protein interacts with another related JNK pathway scaffold protein, WDR62, via a conserved dimerization domain, and enhances JNK signaling. This protein may play a role in bacterial immunity by binding to the NOD2 receptor and negatively regulating downstream antibacterial and pro-inflammatory signaling. Mutations in this gene that impair cellular localization of the encoded protein cause a form of nephronophthisis, an autosomal-recessive kidney disorder, in human patients.,MAPKBP1,JNKBP-1,JNKBP1,NPHP20,Signal Transduction,Kinase,MAPKBP1

Molekulargewicht: 23 kDa/109 kDa/134 kDa/149 kDa/163 kDa

Gen-ID: 23005

UniProt: O60336