RACGAP1 Antikörper (AA 1-110)

Produktnummer ABIN565414

Dieses Maus Monoklonal-Antikörper erkennt spezifisch RACGAP1 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human und wurde in 4+ Publikationen erwähnt.

Kurzübersicht für RACGAP1 Antikörper (AA 1-110) (ABIN565414)

Target: RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RACGAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 1G6

Produktdetails anti-RACGAP1 Antikörper

Bindungsspezifität: AA 1-110

Verwendungszweck: Mouse monoclonal antibody raised against a partial recombinant RACGAP1.

Sequenz: MDTMMLNVRN LFEQLVRRVE ILSEGNEVQF IQLAKDFEDF RKKWQRTDHE LGKYKDLLMK AETERSALDV KLKHARNQVD VEIKRRQRAE ADCEKLERQI QLIREMLMCD

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: RACGAP1 (AAH32754, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-RACGAP1 Antikörper (ABIN565414)

Lekomtsev, Su, Pye, Blight, Sundaramoorthy, Takaki, Collinson, Cherepanov, Divecha, Petronczki: "Centralspindlin links the mitotic spindle to the plasma membrane during cytokinesis." in: Nature, Vol. 492, Issue 7428, pp. 276-9, (2012) (PubMed).

Wang, Ooi, Hui: "Upregulation of Rac GTPase-activating protein 1 is significantly associated with the early recurrence of human hepatocellular carcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 18, pp. 6040-51, (2011) (PubMed).

Wolfe, Takaki, Petronczki, Glotzer: "Polo-like kinase 1 directs assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF complex to initiate cleavage furrow formation." in: PLoS biology, Vol. 7, Issue 5, pp. e1000110, (2009) (PubMed).

Burkard, Maciejowski, Rodriguez-Bravo, Repka, Lowery, Clauser, Zhang, Shokat, Carr, Yaffe, Jallepalli: "Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells." in: PLoS biology, Vol. 7, Issue 5, pp. e1000111, (2009) (PubMed).

Details zu RACGAP1

Target: RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

Andere Bezeichnung: RACGAP1

Hintergrund: Full Gene Name: Rac GTPase activating protein 1
Synonyms: HsCYK-4,ID-GAP,MgcRacGAP

Gen-ID: 29127

Pathways: Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling of Hepatocyte Growth Factor Receptor