GAPDHS Antikörper (AA 1-408)

Produktnummer ABIN565269

Dieses Anti-GAPDHS-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von GAPDHS in WB, ELISA und IHC (p). Geeignet für Human. Dieses Primary Antibody wurde in 12+ Publikationen zitiert.

Kurzübersicht für GAPDHS Antikörper (AA 1-408) (ABIN565269)

Target: GAPDHS (Glyceraldehyde-3-Phosphate Dehydrogenase, Spermatogenic (GAPDHS))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GAPDHS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 2E3-2E10

Produktdetails anti-GAPDHS Antikörper

Bindungsspezifität: AA 1-408

Verwendungszweck: Mouse monoclonal antibody raised against a full length recombinant GAPDS.

Sequenz: MSKRDIVLTN VTVVQLLRQP CPVTRAPPPP EPKAEVEPQP QPEPTPVREE IKPPPPPLPP HPATPPPKMV SVARELTVGI NGFGRIGRLV LRACMEKGVK VVAVNDPFID PEYMVYMFKY DSTHGRYKGS VEFRNGQLVV DNHEISVYQC KEPKQIPWRA VGSPYVVEST GVYLSIQAAS DHISAGAQRV VISAPSPDAP MFVMGVNEND YNPGSMNIVS NASCTTNCLA PLAKVIHERF GIVEGLMTTV HSYTATQKTV DGPSRKAWRD GRGAHQNIIP ASTGAAKAVT KVIPELKGKL TGMAFRVPTP DVSVVDLTCR LAQPAPYSAI KEAVKAAAKG PMAGILAYTE DEVVSTDFLG DTHSSIFDAK AGIALNDNFV KLISWYDNEY GYSHRVVDLL RYMFSRDK

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: GAPDS (AAH36373, 1 a.a. ~ 408 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-GAPDHS Antikörper (ABIN565269)

Kim, Hata, Kang: "Down-regulation of miR-96 by bone morphogenetic protein signaling is critical for vascular smooth muscle cell phenotype modulation." in: Journal of cellular biochemistry, Vol. 115, Issue 5, pp. 889-95, (2014) (PubMed).

Kang, Davis-Dusenbery, Nguyen, Lal, Lieberman, Van Aelst, Lagna, Hata: "Bone morphogenetic protein 4 promotes vascular smooth muscle contractility by activating microRNA-21 (miR-21), which down-regulates expression of family of dedicator of cytokinesis (DOCK) proteins." in: The Journal of biological chemistry, Vol. 287, Issue 6, pp. 3976-86, (2012) (PubMed).

Kuravsky, Schmalhausen, Pozdnyakova, Muronetz: "Isolation of antibodies against different protein conformations using immunoaffinity chromatography." in: Analytical biochemistry, Vol. 426, Issue 1, pp. 47-53, (2012) (PubMed).

Kang, Louie, Weisman, Sheu-Gruttadauria, Davis-Dusenbery, Lagna, Hata: "Inhibition of microRNA-302 (miR-302) by bone morphogenetic protein 4 (BMP4) facilitates the BMP signaling pathway." in: The Journal of biological chemistry, Vol. 287, Issue 46, pp. 38656-64, (2012) (PubMed).

Chan, Weisman, Kang, Nguyen, Hickman, Mecker, Hill, Lagna, Hata: "The amiloride derivative phenamil attenuates pulmonary vascular remodeling by activating NFAT and the bone morphogenetic protein signaling pathway." in: Molecular and cellular biology, Vol. 31, Issue 3, pp. 517-30, (2011) (PubMed).

Davis-Dusenbery, Chan, Reno, Weisman, Layne, Lagna, Hata et al.: "down-regulation of Kruppel-like factor-4 (KLF4) by microRNA-143/145 is critical for modulation of vascular smooth muscle cell phenotype by transforming growth factor-beta and bone morphogenetic ..." in: The Journal of biological chemistry, Vol. 286, Issue 32, pp. 28097-110, (2011) (PubMed).

Chan, Hilyard, Wu, Davis, Hill, Lal, Lieberman, Lagna, Hata: "Molecular basis for antagonism between PDGF and the TGFbeta family of signalling pathways by control of miR-24 expression." in: The EMBO journal, Vol. 29, Issue 3, pp. 559-73, (2010) (PubMed).

Davis, Hilyard, Nguyen, Lagna, Hata: "Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha." in: Molecular cell, Vol. 39, Issue 3, pp. 373-84, (2010) (PubMed).

Elkina, Kuravsky, Eldarov, Stogov, Muronetz, Schmalhausen: "Recombinant human sperm-specific glyceraldehyde-3-phosphate dehydrogenase: structural basis for enhanced stability." in: Biochimica et biophysica acta, Vol. 1804, Issue 12, pp. 2207-12, (2010) (PubMed).

Davis, Hilyard, Nguyen, Lagna, Hata: "Induction of microRNA-221 by platelet-derived growth factor signaling is critical for modulation of vascular smooth muscle phenotype." in: The Journal of biological chemistry, Vol. 284, Issue 6, pp. 3728-38, (2009) (PubMed).

Shchutskaya, Elkina, Kuravsky, Bragina, Schmalhausen: "Investigation of glyceraldehyde-3-phosphate dehydrogenase from human sperms." in: Biochemistry. Biokhimii?a, Vol. 73, Issue 2, pp. 185-91, (2008) (PubMed).

Davis, Hilyard, Lagna, Hata: "SMAD proteins control DROSHA-mediated microRNA maturation." in: Nature, Vol. 454, Issue 7200, pp. 56-61, (2008) (PubMed).

Details zu GAPDHS

Target: GAPDHS (Glyceraldehyde-3-Phosphate Dehydrogenase, Spermatogenic (GAPDHS))

Andere Bezeichnung: GAPDHS

Hintergrund: Full Gene Name: glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
Synonyms: GAPD2,GAPDH-2,GAPDS,HSD-35

Gen-ID: 26330

Pathways: Regulation of Carbohydrate Metabolic Process