AANAT Antikörper (AA 27-54)
Kurzübersicht für AANAT Antikörper (AA 27-54) (ABIN7479786)
Target
Alle AANAT Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 27-54
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Verwendungszweck
- AANAT Antibody
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Aufreinigung
- Antigen affinity
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Immunogen
- A portion of amino acids 27-54 from the human protein was used as the immunogen for this AANAT antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the AANAT antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the AANAT antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- AANAT (Aralkylamine N-Acetyltransferase (AANAT))
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Andere Bezeichnung
- AANAT
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Hintergrund
- Serotonin N-acetyltransferase/AANAT belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome.
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UniProt
- Q16613
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Pathways
- Photoperiodism
Target
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