AANAT Antikörper (AA 27-54)

Produktnummer ABIN5647916

Produktdetails anti-AANAT Antikörper

Target: AANAT (Aralkylamine N-Acetyltransferase (AANAT))

Bindungsspezifität: AA 27-54

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AANAT Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 27-54 from the human protein was used as the immunogen for this AANAT antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the AANAT antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu AANAT

Target: AANAT (Aralkylamine N-Acetyltransferase (AANAT))

Andere Bezeichnung: AANAT (AANAT Produkte)

Synonyme: DSPS antikoerper, SNAT antikoerper, AA-NAT antikoerper, Nat4 antikoerper, Nat-2 antikoerper, Snat antikoerper, aralkylamine N-acetyltransferase antikoerper, arylalkylamine N-acetyltransferase antikoerper, AANAT antikoerper, Aanat antikoerper

Hintergrund: Serotonin N-acetyltransferase/AANAT belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome.

UniProt: Q16613

Pathways: Photoperiodism