AQP11 Antikörper (AA 35-70)

Produktnummer ABIN5647736

Der Kaninchen Polyklonal anti-AQP11 Antikörper (ABIN5647736) detektiert spezifisch AQP11 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für AQP11 Antikörper (AA 35-70) (ABIN5647736)

Target: AQP11 (Aquaporin 11 (AQP11))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AQP11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-AQP11 Antikörper

Bindungsspezifität: AA 35-70

Verwendungszweck: AQP11 Antibody / Aquaporin 11

Aufreinigung: Antigen affinity

Immunogen: Amino acids 35-70 (ARQQLHRPVAHAFVLEFLATFQLCCCTHELQLLSEQ from the human protein were used as the immunogen for the AQP11 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Differences in protocols and secondary/substrate sensitivity may require the AQP11 antibody to be titrated for optimal performance.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the AQP11 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu AQP11

Target: AQP11 (Aquaporin 11 (AQP11))

Andere Bezeichnung: AQP11

Hintergrund: AQP11 has a unique asparagine-proline-alanine (NPA) box distinct from those of other AQPs, suggesting a different pore structure and function. Using Northern blot analysis, they detected highest expression of mouse Aqp11 in testis, followed by liver and kidney. Expression was much weaker in heart, brain, and muscle. Western blot analysis of mouse kidney membrane fractions detected Aqp11 at an apparent molecular mass of 26 kD, lower than the calculated molecular mass of 30 kD. Immunohistochemical analysis localized Aqp11 to mouse renal proximal tubule cells, where it showed a perinuclear distribution. Fluorescence-tagged Aqp11 localized with an endoplasmic reticulum marker.

UniProt: Q8NBQ7