AQP11 Antikörper (AA 35-70)

Produktnummer ABIN5647736

Produktdetails anti-AQP11 Antikörper

Target: AQP11 (Aquaporin 11 (AQP11))

Bindungsspezifität: AA 35-70

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AQP11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids 35-70 (ARQQLHRPVAHAFVLEFLATFQLCCCTHELQLLSEQ from the human protein were used as the immunogen for the AQP11 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the AQP11 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu AQP11

Target: AQP11 (Aquaporin 11 (AQP11))

Andere Bezeichnung: AQP11 / Aquaporin 11 (AQP11 Produkte)

Synonyme: aqpx1 antikoerper, 1700015P13Rik antikoerper, AI648923 antikoerper, sjds antikoerper, AQPX1 antikoerper, aquaporin 11 antikoerper, aquaporin 11 L homeolog antikoerper, AQP11 antikoerper, aqp11 antikoerper, aqp11.L antikoerper, Aqp11 antikoerper

Hintergrund: AQP11 has a unique asparagine-proline-alanine (NPA) box distinct from those of other AQPs, suggesting a different pore structure and function. Using Northern blot analysis, they detected highest expression of mouse Aqp11 in testis, followed by liver and kidney. Expression was much weaker in heart, brain, and muscle. Western blot analysis of mouse kidney membrane fractions detected Aqp11 at an apparent molecular mass of 26 kD, lower than the calculated molecular mass of 30 kD. Immunohistochemical analysis localized Aqp11 to mouse renal proximal tubule cells, where it showed a perinuclear distribution. Fluorescence-tagged Aqp11 localized with an endoplasmic reticulum marker.

UniProt: Q8NBQ7