LGALS1/Galectin 1 Antikörper

Produktnummer ABIN5647567

Der Kaninchen Polyklonal Anti-LGALS1/Galectin 1-Antikörper wurde für WB, IHC (p) und ELISA (Capture) validiert. Er ist geeignet, LGALS1/Galectin 1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für LGALS1/Galectin 1 Antikörper (ABIN5647567)

Target: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LGALS1/Galectin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA (Capture)

Produktdetails anti-LGALS1/Galectin 1 Antikörper

Aufreinigung: Antigen affinity purified

Immunogen: A recombinant rat protein corresponding to amino acids A2-E135 was used as the immunogen for the Galectin 1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Galectin 1 antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,ELISA (Capture, rat recombinant protein): 0.1-0.5 μg/mL (BSA-free format available)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Galectin 1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu LGALS1/Galectin 1

Target: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Andere Bezeichnung: Galectin 1

Hintergrund: Galectin-1 is a protein that in humans is encoded by the LGALS1 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-1 may act as an autocrine negative growth factor that regulates cell proliferation. Galectin-1 expression in Hodgkin Lymphoma has also been shown to mediate immunosuppression of CD8+ T-cells. It is thought to play a role in creating immune tolerance in pregnancy. It has been found that Galectin-1-mediated production of IL6 may assist in augmenting the innate immune response against NiV. Galectin-1 may also be a significant factor that augments the efficiency of the HIV-1 infection process.

UniProt: P11762

Pathways: Carbohydrate Homeostasis