FGA Antikörper (AA 687-727)

Produktnummer ABIN5647558

Der Kaninchen Polyklonal Anti-FGA-Antikörper wurde für WB validiert. Er ist geeignet, FGA in Proben von Human und Ratte zu detektieren.

Kurzübersicht für FGA Antikörper (AA 687-727) (ABIN5647558)

Target: FGA (Fibrinogen alpha Chain (FGA))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FGA Antikörper

Bindungsspezifität: AA 687-727

Kreuzreaktivität (Details): Expected species reactivity: Mouse

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids 687-727 (RTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQRGSVLRVE-human) were used as the immunogen for the Fibrinogen alpha chain antibody. This sequence is specific to the alpha-E isoform and not found in the alpha isoform.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Fibrinogen alpha chain antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Fibrinogen alpha chain antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu FGA

Target: FGA (Fibrinogen alpha Chain (FGA))

Hintergrund: Fibrinogen alpha chain is a protein that in humans is encoded by the FGA gene. This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing.

UniProt: P02671