ACSL6 Antikörper (AA 240-270)

Produktnummer ABIN5647457

Dieses Anti-ACSL6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ACSL6 in WB, ELISA und IHC. Geeignet für Human und Maus.

Kurzübersicht für ACSL6 Antikörper (AA 240-270) (ABIN5647457)

Target: ACSL6 (Acyl-CoA Synthetase Long-Chain Family Member 6 (ACSL6))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACSL6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-ACSL6 Antikörper

Bindungsspezifität: AA 240-270

Aufreinigung: Purified

Immunogen: A portion of amino acids 240-270 from the human protein was used as the immunogen for this ACSL6 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the ACSL6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu ACSL6

Target: ACSL6 (Acyl-CoA Synthetase Long-Chain Family Member 6 (ACSL6))

Andere Bezeichnung: ACSL6 / FACL6

Hintergrund: FACL6 is involved in activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. It plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid. FACL6 is expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derieved from fetal liver, haemopoietic stem cells from cord blood, bone marrow, and brain. Expression is low at earlier stages of erythroid development but is very high in reticulocytes. This protein is involved in myelodysplastic syndrome (MDS) with basophilia, acute myelogenous leukemia (AML) with eosinophilia, and acute eosinophilic leukemia (AEL). It is characterized by a chromosomal translocation t(5,12)(q31,p13) that involves ETV6 and ACSL6.

UniProt: Q9UKU0