APRT Antikörper (AA 5-49)
Kurzübersicht für APRT Antikörper (AA 5-49) (ABIN5647397)
Target
Alle APRT Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 5-49
-
Verwendungszweck
- APRT Antibody / Adenine phosphoribosyltransferase
-
Aufreinigung
- Antigen affinity
-
Immunogen
- Amino acids 5-49 (ELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARH-human) were used as the immunogen for the APRT antibody.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- Optimal dilution of the APRT antibody should be determined by the researcher.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- After reconstitution, the APRT antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- APRT (Adenine Phosphoribosyltransferase (APRT))
-
Andere Bezeichnung
- APRT
-
Hintergrund
- Adenine phosphoribosyltransferase (APRTase) is an enzyme encoded by the APRT gene, found in humans on chromosome 16. It belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.
-
Gen-ID
- 353
-
UniProt
- P07741
-
Pathways
- Ribonucleoside Biosynthetic Process
Target
-