Cytokeratin 5 Antikörper (AA 286-317)

Produktnummer ABIN5647372

Der Kaninchen Polyklonal Anti-Cytokeratin 5-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, Cytokeratin 5 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Cytokeratin 5 Antikörper (AA 286-317) (ABIN5647372)

Target: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cytokeratin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Cytokeratin 5 Antikörper

Bindungsspezifität: AA 286-317

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids 286-317 (KVELEAKVDALMDEINFMKMFFDAELSQMQTH-human) were used as the immunogen for the Cytokeratin 5 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Cytokeratin 5 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Cytokeratin 5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Cytokeratin 5

Target: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Andere Bezeichnung: Cytokeratin 5

Hintergrund: Cytokeratin 5, also known as Keratin 5, KRT5, K5, or CK5, is a protein that is encoded in humans by the KRT5 gene. The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

UniProt: P13647