IL23R Antikörper
Kurzübersicht für IL23R Antikörper (ABIN5647308)
Target
Alle IL23R Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität (Details)
- Expected species reactivity: Human
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Aufreinigung
- Antigen affinity purified
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Immunogen
- A recombinant mouse protein corresponding to amino acids I25-D233 was used as the immunogen for the Il23r antibody.
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Isotyp
- IgG
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Applikationshinweise
- Optimal dilution of the Il23r antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,ELISA (Capture: recombinant mouse protein): 0.1-0.5 μg/mL (BSA-free format available)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Lagerung
- -20 °C
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Informationen zur Lagerung
- After reconstitution, the Il23r antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- IL23R (Interleukin 23 Receptor (IL23R))
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Andere Bezeichnung
- Il-23 receptor / Il23r
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Hintergrund
- Interleukin 23 receptor is a type I cytokine receptor. IL23R is its human gene. The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.
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UniProt
- Q8K4B4
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
Target
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