PNP Antikörper (AA 161-189)
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- Target Alle PNP Antikörper anzeigen
- PNP (Purine Nucleoside Phosphorylase (PNP))
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Bindungsspezifität
- AA 161-189
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PNP Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- Antigen affinity purified
- Immunogen
- Amino acids 161-189 (AMSDAYDRTMRQRALSTWKQMGEQRELQE-human) were used as the immunogen for the Purine nucleoside phosphorylase antibody.
- Isotyp
- IgG
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anti-Purine Nucleoside Phosphorylase (PNP) (AA 161-189), (Middle Region) antibody
PNP Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 1-289) antibodyPNP Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 6E5 unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 1-289) antibodyPNP Reaktivität: Ratte WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 1-289) antibodyPNP Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 174-283) antibodyPNP Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 142-153) antibodyVerified PNP Reaktivität: Human WB, ELISA, IHC Wirt: Ziege Polyclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 68-289) antibodyPNP Reaktivität: Human WB, ELISA, IHC, IHC (p) Wirt: Maus Monoclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 1-289) antibodyPNP Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 145-178) antibodyPNP Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB49601 unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 107-156) antibodyPNP Reaktivität: Human, Rind (Kuh), Huhn, Hund, Affe, Schwein, Kaninchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Optimal dilution of the Purine nucleoside phosphorylase antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL,Flow cytometry: 1-3 μg/10^6 cells
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Lagerung
- -20 °C
- Informationen zur Lagerung
- After reconstitution, the Purine nucleoside phosphorylase antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Target
- PNP (Purine Nucleoside Phosphorylase (PNP))
- Andere Bezeichnung
- PNP / Purine Nucleoside Phosphorylase (PNP Produkte)
- Substanzklasse
- Viral Protein
- Hintergrund
- The PNP gene encodes Purine nucleoside phosphorylase, an enzyme that catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. It is presented results from gene dosage studies consistent with assignment of the PNP locus to band 14q13. PNP is expressed in most tissues, with markedly greater expression in lymphoid tissues. Genetic deficiencies of PNP result in severely compromised T?lymphocyte function and neurologic dysfunction.
- UniProt
- P00491
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus
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