Muscarinic Acetylcholine Receptor M2 Antikörper (AA 352-376)

Produktnummer ABIN5647209

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Muscarinic Acetylcholine Receptor M2 in WB. Er zeigt eine Reaktivität gegenüber Maus und Ratte.

Kurzübersicht für Muscarinic Acetylcholine Receptor M2 Antikörper (AA 352-376) (ABIN5647209)

Target: Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Muscarinic Acetylcholine Receptor M2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Muscarinic Acetylcholine Receptor M2 Antikörper

Bindungsspezifität: AA 352-376

Kreuzreaktivität (Details): Expected species reactivity: Human

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids 352-376 (QNGDEKQNIVARKIVKMTKQPAKKK) from the human protein were used as the immunogen for the CHRM2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CHRM2 antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the CHRM2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Muscarinic Acetylcholine Receptor M2

Target: Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))

Andere Bezeichnung: CHRM2

Hintergrund: The muscarinic acetylcholine receptor M2, also known as the cholinergic receptor, muscarinic 2, is a muscarinic acetylcholine receptor that in humans is encoded by the CHRM2 gene. The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.

UniProt: P08172