IL17F Antikörper

Produktnummer ABIN5647177

Der Kaninchen Polyklonal Anti-IL17F-Antikörper wurde für WB und ELISA (Capture) validiert. Er ist geeignet, IL17F in Proben von Maus und Ratte zu detektieren.

Kurzübersicht für IL17F Antikörper (ABIN5647177)

Target: IL17F (Interleukin 17F (IL17F))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL17F Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA (Capture)

Produktdetails anti-IL17F Antikörper

Aufreinigung: Antigen affinity purified

Immunogen: A recombinant mouse protein corresponding to amino acids R29-A161 was used as the immunogen for the IL17F antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the IL17F antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,ELISA (Capture, recombinant mouse protein): 0.1-0.5 μg/mL (BSA-free format available)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the IL17F antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu IL17F

Target: IL17F (Interleukin 17F (IL17F))

Andere Bezeichnung: IL-17F

Hintergrund: Interleukin 17F, also called IL17F is involved in the regulation of normal versus aberrant T-cell responses. This gene is mapped to 6p12.2. The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. It is suggested that targeting IL17 and IL17F or antagonizing IL17R might mitigate neutrophil-mediated inflammation in CF.

UniProt: Q7TNI7

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity