INTS6
Reaktivität: Human
ELISA
Wirt: Kaninchen
Polyclonal
Biotin
Applikationshinweise
Western blot: 1:1000-2000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the INTS6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
INTS6
(Integrator Complex Subunit 6 (INTS6))
Andere Bezeichnung
INTS6 / DICE1
Hintergrund
Integrator complex subunit 6 is a component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. May have a tumor suppressor role, an ectopic expression suppressing tumor cell growth.