AIRE Antikörper
Kurzübersicht für AIRE Antikörper (ABIN5647007)
Target
Alle AIRE Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Antigen affinity purified
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Immunogen
- Amino acids M1-K120 from the human protein were used as the immunogen for the AIRE antibody.
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Isotyp
- IgG
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Applikationshinweise
- Western blot: 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Prior to reconstitution, store at 4°C. After reconstitution, the AIRE antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- AIRE (Autoimmune Regulator (AIRE))
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Andere Bezeichnung
- AIRE
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Hintergrund
- The autoimmune regulator (AIRE) is a protein that in humans is encoded by the AIRE gene. This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).
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UniProt
- O43918
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Pathways
- Chromatin Binding
Target
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