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Dynamin 1-Like Antikörper (AA 1-710)

Der Maus Monoklonal Anti-Dynamin 1-Like-Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet, Dynamin 1-Like in Proben von Human zu detektieren. Es sind 4+ Publikationen verfügbar.
Produktnummer ABIN564347

Kurzübersicht für Dynamin 1-Like Antikörper (AA 1-710) (ABIN564347)

Target

Alle Dynamin 1-Like (DNM1L) Antikörper anzeigen
Dynamin 1-Like (DNM1L)

Reaktivität

  • 58
  • 46
  • 30
  • 5
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 67
  • 12
Maus

Klonalität

  • 65
  • 14
Monoklonal

Konjugat

  • 42
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Dynamin 1-Like Antikörper ist unkonjugiert

Applikation

  • 44
  • 32
  • 25
  • 17
  • 13
  • 13
  • 10
  • 7
  • 6
  • 6
  • 3
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

3B5
  • Bindungsspezifität

    • 24
    • 11
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-710

    Verwendungszweck

    Mouse monoclonal antibody raised against a full length recombinant DNM1L.

    Sequenz

    MEALIPVINK LQDVFNTVGA DIIQLPQIVV VGTQSSGKSS VLESLVGRDL LPRGTGIVTR RPLILQLVHV SQEDKRKTTG EENGVEAEEW GKFLHTKNKL YTDFDEIRQE IENETERISG NNKGVSPEPI HLKIFSPNVV NLTLVDLPGM TKVPVGDQPK DIELQIRELI LRFISNPNSI ILAVTAANTD MATSEALKIS REVDPDGRRT LAVITKLDLM DAGTDAMDVL MGRVIPVKLG IIGVVNRSQL DINNKKSVTD SIRDEYAFLQ KKYPSLANRN GTKYLARTLN RLLMHHIRDC LPELKTRINV LAAQYQSLLN SYGEPVDDKS ATLLQLITKF ATEYCNTIEG TAKYIETSEL CGGARICYIF HETFGRTLES VDPLGGLNTI DILTAIRNAT GPRPALFVPE VSFELLVKRQ IKRLEEPSLR CVELVHEEMQ RIIQHCSNYS TQELLRFPKL HDAIVEVVTC LLRKRLPVTN EMVHNLVAIE LAYINTKHPD FADACGLMNN NIEEQRRNRL ARELPSAVSR DKLIQDSRRE TKNVASGGGG VGDGVQEPTT GNWRGMLKTS KAEELLAEEK SKPIPIMPAS PQKGHAVNLL DVPVPVARKL SAREQRDCEV IERLIKSYFL IVRKNIQDSV PKAVMHFLVN HVKDTLQSEL VGQLYKSSLL DDLLTESEDM AQRRKEAADM LKALQGASQI IAEIRETHLW

    Kreuzreaktivität

    Human

    Produktmerkmale

    Antibody Reactive Against Recombinant Protein.

    Immunogen

    DNM1L (AAH24590.1, 1 a.a. ~ 710 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    Isotyp

    IgG2b
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    In 1x PBS, pH 7.4

    Handhabung

    Aliquot to avoid repeated freezing and thawing.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Kim, McLean, Philip, Feldman: "Hyperinsulinemia induces insulin resistance in dorsal root ganglion neurons." in: Endocrinology, Vol. 152, Issue 10, pp. 3638-47, (2011) (PubMed).

    Edwards, Quattrini, Lentz, Figueroa-Romero, Cerri, Backus, Hong, Feldman: "Diabetes regulates mitochondrial biogenesis and fission in mouse neurons." in: Diabetologia, Vol. 53, Issue 1, pp. 160-9, (2010) (PubMed).

    Vincent, Edwards, McLean, Hong, Cerri, Lopez, Quattrini, Feldman: "Mitochondrial biogenesis and fission in axons in cell culture and animal models of diabetic neuropathy." in: Acta neuropathologica, Vol. 120, Issue 4, pp. 477-89, (2010) (PubMed).

    Figueroa-Romero, Iñiguez-Lluhí, Stadler, Chang, Arnoult, Keller, Hong, Blackstone, Feldman: "SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycle." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 11, pp. 3917-27, (2009) (PubMed).

  • Target

    Dynamin 1-Like (DNM1L)

    Andere Bezeichnung

    DNM1L

    Hintergrund

    Full Gene Name: dynamin 1-like
    Synonyms: DLP1,DRP1,DVLP,DYMPLE,DYNIV-11,FLJ41912,HDYNIV,VPS1

    Gen-ID

    10059
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