Topoisomerase I Antikörper (AA 692-765)
Kurzübersicht für Topoisomerase I Antikörper (AA 692-765) (ABIN563222)
Target
Alle Topoisomerase I (TOP1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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    - 
                                            Bindungsspezifität
- AA 692-765
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                                            Verwendungszweck
- Mouse monoclonal antibody raised against a partial recombinant TOP1.
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                                            Sequenz
- QRLEEQLMKL EVQATDREEN KQIALGTSKL NYLDPRITVA WCKKWGVPIE KIYNKTQREK FAWAIDMADE DYEF
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                                            Kreuzreaktivität
- Human
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                                            Produktmerkmale
- Antibody Reactive Against Recombinant Protein.
- 
                                            Immunogen
- TOP1 (NP_003277, 692 a.a. ~ 765 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- 
                                            Isotyp
- IgG1
 
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    - 
                                            Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Buffer
- In 1x PBS, pH 7.4
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                                            Handhabung
- Aliquot to avoid repeated freezing and thawing.
- 
                                            Lagerung
- -20 °C
- 
                                            Informationen zur Lagerung
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
 
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- 
    - 
                                            : "AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination."    in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 52, pp. 22375-80, (2010)         (PubMed).        
 
 
- 
                                            : "AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination."    in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 52, pp. 22375-80, (2010)         (PubMed).        
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    - Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))
- 
                                            Andere Bezeichnung
- TOP1
- 
                                            Hintergrund
- 
                        Full Gene Name: topoisomerase (DNA) I
 Synonyms: TOPI
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                                            Gen-ID
- 7150
- 
                                            NCBI Accession
- NM_003286
- 
                                            Pathways
- Caspase Kaskade in der Apoptose, Stem Cell Maintenance
 Target
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