Topoisomerase I Antikörper (AA 692-765)
Kurzübersicht für Topoisomerase I Antikörper (AA 692-765) (ABIN563222)
Target
Alle Topoisomerase I (TOP1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 692-765
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Verwendungszweck
- Mouse monoclonal antibody raised against a partial recombinant TOP1.
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Sequenz
- QRLEEQLMKL EVQATDREEN KQIALGTSKL NYLDPRITVA WCKKWGVPIE KIYNKTQREK FAWAIDMADE DYEF
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Kreuzreaktivität
- Human
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Produktmerkmale
- Antibody Reactive Against Recombinant Protein.
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Immunogen
- TOP1 (NP_003277, 692 a.a. ~ 765 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Isotyp
- IgG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- In 1x PBS, pH 7.4
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Handhabung
- Aliquot to avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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: "AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 52, pp. 22375-80, (2010) (PubMed).
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: "AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 52, pp. 22375-80, (2010) (PubMed).
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- Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))
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Andere Bezeichnung
- TOP1
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Hintergrund
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Full Gene Name: topoisomerase (DNA) I
Synonyms: TOPI -
Gen-ID
- 7150
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NCBI Accession
- NM_003286
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Pathways
- Caspase Kaskade in der Apoptose, Stem Cell Maintenance
Target
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