Progesterone Receptor Antikörper (AA 1-110)

Produktnummer ABIN562204

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Progesterone Receptor in WB, ELISA, IHC (p) und IF. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für Progesterone Receptor Antikörper (AA 1-110) (ABIN562204)

Target: Progesterone Receptor (PGR)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Progesterone Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Klon: 5D10

Produktdetails anti-Progesterone Receptor Antikörper

Bindungsspezifität: AA 1-110

Verwendungszweck: Mouse monoclonal antibody raised against a partial recombinant PGR. This PGR gene uses two distinct promoters and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B. Our immunogen corresponds to the specific region of isoform B, thus this antibody is a PGR isofrom B specific antibody.

Sequenz: MTELKAKGPR APHVAGGPPS PEVGSPLLCR PAAGPFPGSQ TSDTLPEVSA IPISLDGLLF PRPCQGQDPS DEKTQDQQSL SDVEGAYSRA EATRGAGGSS SSPPEKDSGL

Kreuzreaktivität: Human, Ratte

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: PGR (NP_000917, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-Progesterone Receptor Antikörper (ABIN562204)

Liu, Chang, Kuo, Hwa, Lin, Huang, Chen, Chang, Hsieh: "Major Functional Transcriptome of an Inferred Center Regulator of an ER(-) Breast Cancer Model System." in: Cancer informatics, Vol. 11, pp. 87-111, (2012) (PubMed).

Liu, Chang, Kuo, Hwa, Shyu, Chang, Hsieh: "In Silico Prediction for Regulation of Transcription Factors onTheir Shared Target Genes Indicates Relevant Clinical Implications in a Breast Cancer Population." in: Cancer informatics, Vol. 11, pp. 113-37, (2012) (PubMed).

Details zu Progesterone Receptor

Target: Progesterone Receptor (PGR)

Andere Bezeichnung: PGR

Hintergrund: Full Gene Name: progesterone receptor
Synonyms: NR3C3,PR

Gen-ID: 5241

NCBI Accession: NM_000926

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration