PCBP2 Antikörper (AA 1-362)

Produktnummer ABIN562121

Produktdetails anti-PCBP2 Antikörper

Target: PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))

Bindungsspezifität: AA 1-362

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PCBP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)

Verwendungszweck: Mouse monoclonal antibody raised against a full length recombinant PCBP2.

Sequenz: MDTGVIEGGL NVTLTIRLLM HGKEVGSIIG KKGESVKKMR EESGARINIS EGNCPERIIT LAGPTNAIFK AFAMIIDKLE EDISSSMTNS TAASRPPVTL RLVVPASQCG SLIGKGGCKI KEIRESTGAQ VQVAGDMLPN STERAITIAG IPQSIIECVK QICVVMLESP PKGVTIPYRP KPSSSPVIFA GGQDRYSTGS DSASFPHTTP SMCLNPDLEG PPLEAYTIQG QYAIPQPDLT KLHQLAMQQS HFPMTHGNTG FSGIESSSPE VKGYWAGLDA SAQTTSHELT IPNDLIGCII GRQGAKINEI RQMSGAQIKI ANPVEGSTDR QVTITGSAAS ISLAQYLINV RLSSETGGMG SS

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: PCBP2 (AAH01155, 1 a.a. ~ 362 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon: 5F12

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-PCBP2 Antikörper (ABIN562121)

Yanatori, Richardson, Imada, Kishi: "Iron Export through the Transporter Ferroportin 1 Is Modulated by the Iron Chaperone PCBP2." in: The Journal of biological chemistry, Vol. 291, Issue 33, pp. 17303-18, (2016) (PubMed).

Li, Masaki, Shimakami, Lemon: "hnRNP L and NF90 interact with hepatitis C virus 5'-terminal untranslated RNA and promote efficient replication." in: Journal of virology, Vol. 88, Issue 13, pp. 7199-209, (2014) (PubMed).

Fujimura, Sasaki, Anderson: "Selenite targets eIF4E-binding protein-1 to inhibit translation initiation and induce the assembly of non-canonical stress granules." in: Nucleic acids research, Vol. 40, Issue 16, pp. 8099-110, (2012) (PubMed).

Wang, Jeng, Lai et al.: "Poly(C)-binding protein 2 interacts with sequences required for viral replication in the hepatitis C virus (HCV) 5' untranslated region and directs HCV RNA replication through circularizing the viral ..." in: Journal of virology, Vol. 85, Issue 16, pp. 7954-64, (2011) (PubMed).

Süss, Czupalla, Winter, Pursche, Knoch, Schroeder, Hoflack, Solimena: "Rapid changes of mRNA-binding protein levels following glucose and 3-isobutyl-1-methylxanthine stimulation of insulinoma INS-1 cells." in: Molecular & cellular proteomics : MCP, Vol. 8, Issue 3, pp. 393-408, (2009) (PubMed).

Fujimura, Katahira, Kano, Yoneda, Murata: "Selective localization of PCBP2 to cytoplasmic processing bodies." in: Biochimica et biophysica acta, Vol. 1793, Issue 5, pp. 878-87, (2009) (PubMed).

Lawrence, Rieder: "Identification of RNA helicase A as a new host factor in the replication cycle of foot-and-mouth disease virus." in: Journal of virology, Vol. 83, Issue 21, pp. 11356-66, (2009) (PubMed).

Fujimura, Kano, Murata: "Identification of PCBP2, a facilitator of IRES-mediated translation, as a novel constituent of stress granules and processing bodies." in: RNA (New York, N.Y.), Vol. 14, Issue 3, pp. 425-31, (2008) (PubMed).

Ghosh, Srivastava, Xu, Schulz, Roberts: "A link between SIN1 (MAPKAP1) and poly(rC) binding protein 2 (PCBP2) in counteracting environmental stress." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 33, pp. 11673-8, (2008) (PubMed).

Details zu PCBP2

Target: PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))

Andere Bezeichnung: PCBP2 (PCBP2 Produkte)

Hintergrund: Full Gene Name: poly(rC) binding protein 2
Synonyms: HNRPE2,MGC110998,hnRNP-E2

Gen-ID: 5094