LETM1 Antikörper (AA 601-708)

Produktnummer ABIN561659

Der Maus Monoklonal Anti-LETM1-Antikörper wurde für WB, ELISA, IF, IP und IHC (p) validiert. Er ist geeignet, LETM1 in Proben von Human zu detektieren. Es sind 6+ Publikationen verfügbar.

Kurzübersicht für LETM1 Antikörper (AA 601-708) (ABIN561659)

Target: LETM1 (Leucine Zipper-EF-Hand Containing Transmembrane Protein 1 (LETM1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LETM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 6F7

Produktdetails anti-LETM1 Antikörper

Bindungsspezifität: AA 601-708

Verwendungszweck: Mouse monoclonal antibody raised against a partial recombinant LETM1.

Sequenz: ESKASKRLTK RVQQMIGQID GLISQLEMDQ QAGKLAPANG MPTGENVISV AELINAMKQV KHIPESKLTS LAAALDENKD GKVNIDDLVK VIELVDKEDV HISTSQVA

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: LETM1 (NP_036450, 601 a.a. ~ 708 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-LETM1 Antikörper (ABIN561659)

Chen, Yang, Liu, Piao, Zhang, Lin, Li: "High expression of leucine zipper-EF-hand containing transmembrane protein 1 predicts poor prognosis in head and neck squamous cell carcinoma." in: BioMed research international, Vol. 2014, pp. 850316, (2014) (PubMed).

Doonan, Chandramoorthy, Hoffman, Zhang, Cárdenas, Shanmughapriya, Rajan, Vallem, Chen, Foskett, Cheung, Houser, Madesh: "LETM1-dependent mitochondrial Ca2+ flux modulates cellular bioenergetics and proliferation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 11, pp. 4936-49, (2014) (PubMed).

Shin, Chung, Kang, Jiang, Yu, Han, Chae, Moon, Jang, Cho: "Co-delivery of LETM1 and CTMP synergistically inhibits tumor growth in H-ras12V liver cancer model mice." in: Cancer gene therapy, Vol. 20, Issue 3, pp. 186-94, (2013) (PubMed).

Piao, Li, Kim, Sohn, Yang, Park, Byun, Won, Hong, Hur, Seok, Shong, Sack, Brazil, Hemmings, Park: "Regulation of OPA1-mediated mitochondrial fusion by leucine zipper/EF-hand-containing transmembrane protein-1 plays a role in apoptosis." in: Cellular signalling, Vol. 21, Issue 5, pp. 767-77, (2009) (PubMed).

Piao, Li, Kim, Byun, Huang, Hwang, Yang, Park, Won, Hong, Hur, Seok, Shong, Cho, Brazil, Hemmings, Park: "Association of LETM1 and MRPL36 contributes to the regulation of mitochondrial ATP production and necrotic cell death." in: Cancer research, Vol. 69, Issue 8, pp. 3397-404, (2009) (PubMed).

Dimmer, Navoni, Casarin, Trevisson, Endele, Winterpacht, Salviati, Scorrano: "LETM1, deleted in Wolf-Hirschhorn syndrome is required for normal mitochondrial morphology and cellular viability." in: Human molecular genetics, Vol. 17, Issue 2, pp. 201-14, (2008) (PubMed).

Details zu LETM1

Target: LETM1 (Leucine Zipper-EF-Hand Containing Transmembrane Protein 1 (LETM1))

Andere Bezeichnung: LETM1

Hintergrund: Full Gene Name: leucine zipper-EF-hand containing transmembrane protein 1
Synonyms:

Gen-ID: 3954

NCBI Accession: NM_012318