Dieses Maus Monoklonal-Antikörper erkennt spezifisch H3F3B in WB, ELISA, IF und IHC (p). Er zeigt eine Reaktivität gegenüber Human und wurde in 6+ Publikationen erwähnt.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
In 1x PBS, pH 7.4
Handhabung
Aliquot to avoid repeated freezing and thawing.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Hammoud, Low, Yi, Carrell, Guccione, Cairns: "Chromatin and transcription transitions of mammalian adult germline stem cells and spermatogenesis." in: Cell stem cell, Vol. 15, Issue 2, pp. 239-53, (2014) (PubMed).
Jullien, Astrand, Szenker, Garrett, Almouzni, Gurdon: "HIRA dependent H3.3 deposition is required for transcriptional reprogramming following nuclear transfer to Xenopus oocytes." in: Epigenetics & chromatin, Vol. 5, Issue 1, pp. 17, (2013) (PubMed).
Orsi, Algazeery, Meyer, Capri, Sapey-Triomphe, Horard, Gruffat, Couble, Aït-Ahmed, Loppin: "Drosophila Yemanuclein and HIRA cooperate for de novo assembly of H3.3-containing nucleosomes in the male pronucleus." in: PLoS genetics, Vol. 9, Issue 2, pp. e1003285, (2013) (PubMed).
Lin, Conti, Ramalho-Santos: "Histone variant H3.3 maintains a decondensed chromatin state essential for mouse preimplantation development." in: Development (Cambridge, England), Vol. 140, Issue 17, pp. 3624-34, (2013) (PubMed).
Szenker, Lacoste, Almouzni: "A developmental requirement for HIRA-dependent H3.3 deposition revealed at gastrulation in Xenopus." in: Cell reports, Vol. 1, Issue 6, pp. 730-40, (2012) (PubMed).
Drané, Ouararhni, Depaux, Shuaib, Hamiche: "The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3." in: Genes & development, Vol. 24, Issue 12, pp. 1253-65, (2010) (PubMed).
Target
H3F3B
(H3 Histone, Family 3B (H3.3B) (H3F3B))
Andere Bezeichnung
H3F3B
Hintergrund
Full Gene Name: H3 histone, family 3B (H3.3B) Synonyms: H3.3B,H3F3A