GLRB Antikörper (AA 23-160)
Kurzübersicht für GLRB Antikörper (AA 23-160) (ABIN5611340)
Target
Alle GLRB Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 23-160
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Verwendungszweck
- GLRB Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human GLRB (AA: 23-160) expressed in E. Coli.
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Isotyp
- IgG2b
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- GLRB (Glycine Receptor, beta (GLRB))
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Andere Bezeichnung
- GLRB
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Hintergrund
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This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.
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Molekulargewicht
- 56.1 kDa
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Gen-ID
- 2743
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UniProt
- P48167
Target
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