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Estrogen Receptor alpha Antikörper (pTyr537)

ESR1 Reaktivität: Human ELISA, FACS Wirt: Maus Monoclonal 3C6C6 unconjugated
Produktnummer ABIN5611310
  • Target Alle Estrogen Receptor alpha (ESR1) Antikörper anzeigen
    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
    Bindungsspezifität
    • 30
    • 28
    • 28
    • 26
    • 22
    • 21
    • 16
    • 16
    • 16
    • 16
    • 16
    • 15
    • 15
    • 12
    • 11
    • 10
    • 9
    • 9
    • 9
    • 8
    • 7
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    pTyr537
    Reaktivität
    • 464
    • 167
    • 160
    • 17
    • 16
    • 10
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 374
    • 97
    • 1
    • 1
    Maus
    Klonalität
    • 357
    • 117
    • 1
    Monoklonal
    Konjugat
    • 213
    • 32
    • 21
    • 19
    • 15
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    Dieser Estrogen Receptor alpha Antikörper ist unkonjugiert
    Applikation
    • 342
    • 157
    • 139
    • 112
    • 94
    • 84
    • 80
    • 54
    • 31
    • 28
    • 23
    • 15
    • 9
    • 7
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS)
    Verwendungszweck
    Phospho-Eralpha (Tyr-537) Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Synthesized peptide of human Eralpha(AA: 530-542 (Tyr-537)) expressed in E. Coli.
    Klon
    3C6C6
    Isotyp
    IgG1
    Top Product
    Discover our top product ESR1 Primärantikörper
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
    Andere Bezeichnung
    Eralpha (ESR1 Produkte)
    Hintergrund

    Description: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.

    Aliases: ESR1,ER, ESR, Era, ESRA, ESTRR, NR3A1

    Molekulargewicht
    66.2kDa
    Gen-ID
    2099
    HGNC
    2099
    UniProt
    P03372
    Pathways
    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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