CHRNA4 Antikörper (AA 29-242)

Produktnummer ABIN5611309

Dieses Anti-CHRNA4-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CHRNA4 in ELISA. Geeignet für Human.

Kurzübersicht für CHRNA4 Antikörper (AA 29-242) (ABIN5611309)

Target: CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CHRNA4 Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 7B4H1

Produktdetails anti-CHRNA4 Antikörper

Bindungsspezifität: AA 29-242

Verwendungszweck: CHRNA4 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human CHRNA4 (AA: 29-242) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu CHRNA4

Target: CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Andere Bezeichnung: CHRNA4

Hintergrund: This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 70 kDa

Gen-ID: 1137

UniProt: P43681

Pathways: Synaptic Membrane