Neuropilin 1 Antikörper (AA 22-644)
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- Target Alle Neuropilin 1 (NRP1) Antikörper anzeigen
- Neuropilin 1 (NRP1)
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Bindungsspezifität
- AA 22-644
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Neuropilin 1 Antikörper ist unkonjugiert
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Applikation
- ELISA
- Verwendungszweck
- NRP1 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human NRP1 (AA: 22-644) expressed in HEK293 cells.
- Klon
- 5H11G6
- Isotyp
- IgG1
- Top Product
- Discover our top product NRP1 Primärantikörper
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- Applikationshinweise
- ELISA: 1/10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- Neuropilin 1 (NRP1)
- Andere Bezeichnung
- NRP1 (NRP1 Produkte)
- Hintergrund
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This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors, they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
- Molekulargewicht
- 103.1 kDa
- Gen-ID
- 8829
- UniProt
- O14786
- Pathways
- Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
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