Neuropilin 1 Antikörper (AA 22-644)

Produktnummer ABIN5611190

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Neuropilin 1 in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Neuropilin 1 Antikörper (AA 22-644) (ABIN5611190)

Target: Neuropilin 1 (NRP1)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Neuropilin 1 Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 5H11G6

Produktdetails anti-Neuropilin 1 Antikörper

Bindungsspezifität: AA 22-644

Verwendungszweck: NRP1 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human NRP1 (AA: 22-644) expressed in HEK293 cells.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu Neuropilin 1

Target: Neuropilin 1 (NRP1)

Andere Bezeichnung: NRP1

Hintergrund: This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors, they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Molekulargewicht: 103.1 kDa

Gen-ID: 8829

UniProt: O14786

Pathways: Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals