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Metabotropic Glutamate Receptor 3 Antikörper (AA 433-576)

GRM3 Reaktivität: Human WB, ELISA, IHC, FACS, ICC Wirt: Maus Monoclonal 7A5A6 unconjugated
Produktnummer ABIN5611177
  • Target Alle Metabotropic Glutamate Receptor 3 (GRM3) Antikörper anzeigen
    Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))
    Bindungsspezifität
    • 16
    • 10
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 433-576
    Reaktivität
    • 40
    • 31
    • 14
    • 11
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    Human
    Wirt
    • 55
    • 1
    • 1
    Maus
    Klonalität
    • 55
    • 2
    Monoklonal
    Konjugat
    • 24
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Metabotropic Glutamate Receptor 3 Antikörper ist unkonjugiert
    Applikation
    • 44
    • 19
    • 16
    • 9
    • 9
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human GRM3 (AA: extra 433-576) expressed in E. coli.
    Klon
    7A5A6
    Isotyp
    IgG2a
    Top Product
    Discover our top product GRM3 Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400, IHC: 1:200 - 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Target
    Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))
    Andere Bezeichnung
    GRM3 (GRM3 Produkte)
    Synonyme
    GLUR3 antikoerper, GPRC1C antikoerper, MGLUR3 antikoerper, mGlu3 antikoerper, 0710001G23Rik antikoerper, Gprc1c antikoerper, mGluR3 antikoerper, glutamate metabotropic receptor 3 antikoerper, glutamate receptor, metabotropic 3 antikoerper, GRM3 antikoerper, Grm3 antikoerper
    Hintergrund

    Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

    Aliases: GLUR3, mGlu3, GPRC1C, MGLUR3

    Molekulargewicht
    99 kDa
    Gen-ID
    2913
    HGNC
    2913
    Pathways
    cAMP Metabolic Process, Synaptic Membrane
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