Metabotropic Glutamate Receptor 3 Antikörper (AA 433-576)
Kurzübersicht für Metabotropic Glutamate Receptor 3 Antikörper (AA 433-576) (ABIN5611177)
Target
Alle Metabotropic Glutamate Receptor 3 (GRM3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 433-576
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Verwendungszweck
- GRM3 Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human GRM3 (AA: 433-576) expressed in E. Coli.
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Isotyp
- IgG2a
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anti-Glutamate Receptor, Metabotropic 3 (GRM3) (AA 433-576) antibody
GRM3 Reaktivität: Human ELISA, IHC, FACS Wirt: Maus Monoclonal 6H10C3 unconjugated
anti-Glutamate Receptor, Metabotropic 3 (GRM3) (N-Term) antibodyGRM3 Reaktivität: Human, Rind (Kuh), Pferd, Affe, Schwein WB, IHC, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 3 (GRM3) (N-Term) antibodyGRM3 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Affe, Hamster, Schwein IHC, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 3 (GRM3) (AA 23-170) antibodyGRM3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 3 (GRM3) (C-Term) antibodyGRM3 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 3 (GRM3) (AA 24-38), (Extracellular) antibodyKO Validated GRM3 Reaktivität: Ratte WB, IHC, IF, IC, LCI Wirt: Kaninchen Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 3 (GRM3) (AA 46-354) antibodyGRM3 Reaktivität: Human ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 3 (GRM3) antibodyGRM3 Reaktivität: Human, Maus, Ratte ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 3 (GRM3) (AA 828-857), (C-Term) antibodyGRM3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB4623 unconjugated
anti-Glutamate Receptor, Metabotropic 3 (GRM3) (AA 568-819) antibodyGRM3 Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))
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Andere Bezeichnung
- GRM3
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Hintergrund
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L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
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Molekulargewicht
- 99 kDa
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Gen-ID
- 2913
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UniProt
- Q14832
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Pathways
- cAMP Metabolic Process, Synaptic Membrane
Target
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