GRM7 Antikörper (AA 454-590)

Produktnummer ABIN5611161

Der Maus Monoklonal Anti-GRM7-Antikörper wurde für ELISA, FACS und ICC validiert. Er ist geeignet, GRM7 in Proben von Human zu detektieren.

Kurzübersicht für GRM7 Antikörper (AA 454-590) (ABIN5611161)

Target: GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GRM7 Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Klon: 7G8D3

Produktdetails anti-GRM7 Antikörper

Bindungsspezifität: AA 454-590

Verwendungszweck: GRM7 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human GRM7 (AA: 454-590) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu GRM7

Target: GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))

Andere Bezeichnung: GRM7

Hintergrund: L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 102.3 kDa

Gen-ID: 2917

UniProt: Q14831

Pathways: Sensory Perception of Sound, cAMP Metabolic Process, Feeding Behaviour