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BCR Antikörper (AA 139-280)

Dieses Anti-BCR-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von BCR in WB, ELISA und FACS. Geeignet für Human.
Produktnummer ABIN5611129

Kurzübersicht für BCR Antikörper (AA 139-280) (ABIN5611129)

Target

Alle BCR Antikörper anzeigen
BCR (Breakpoint Cluster Region (BCR))

Reaktivität

  • 98
  • 56
  • 26
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 94
  • 4
  • 3
Maus

Klonalität

  • 97
  • 4
Monoklonal

Konjugat

  • 61
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser BCR Antikörper ist unkonjugiert

Applikation

  • 72
  • 37
  • 33
  • 27
  • 26
  • 26
  • 19
  • 15
  • 14
  • 11
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Klon

1E11G12
  • Bindungsspezifität

    • 30
    • 16
    • 8
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 139-280

    Verwendungszweck

    BCR Antibody

    Aufreinigung

    Purified antibody

    Immunogen

    Purified recombinant fragment of human BCR (AA: 139-280) expressed in E. Coli.

    Isotyp

    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified antibody in PBS with 0.05 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target

    BCR (Breakpoint Cluster Region (BCR))

    Andere Bezeichnung

    BCR

    Hintergrund

    A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.

    Molekulargewicht

    142.8 kDa

    Gen-ID

    613

    UniProt

    P11274

    Pathways

    Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling
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