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GART Antikörper (AA 1-433)

Dieses Maus Monoklonal-Antikörper erkennt spezifisch GART in WB, ELISA, IF, IP und IHC (p). Er zeigt eine Reaktivität gegenüber Human und wurde in 5+ Publikationen erwähnt.
Produktnummer ABIN560998

Kurzübersicht für GART Antikörper (AA 1-433) (ABIN560998)

Target

GART (Phosphoribosylglycinamide Formyltransferase (GART))

Reaktivität

  • 48
  • 25
  • 13
  • 2
Human

Wirt

  • 46
  • 3
Maus

Klonalität

  • 38
  • 11
Monoklonal

Konjugat

  • 21
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser GART Antikörper ist unkonjugiert

Applikation

  • 19
  • 14
  • 13
  • 7
  • 6
  • 5
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

4D6-1D5
  • Bindungsspezifität

    • 15
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-433

    Verwendungszweck

    Mouse monoclonal antibody raised against a full length recombinant GART.

    Sequenz

    MAARVLIIGS GGREHTLAWK LAQSHHVKQV LVAPGNAGTA CSEKISNTAI SISDHTALAQ FCKEKKIEFV VVGPEAPLAA GIVGNLRSAG VQCFGPTAEA AQLESSKRFA KEFMDRHGIP TAQWKAFTKP EEACSFILSA DFPALVVKAS GLAAGKGVIV AKSKEEACKA VQEIMQEKAF GAAGETIVIE ELLDGEEVSC LCFTDGKTVA PMPPAQDHKR LLEGDGGPNT GGMGAYCPAP QVSNDLLLKI KDTVLQRTVD GMQQEGTPYT GILYAGIMLT KNGPKVLEFN CRFGDPECQV ILPLLKSDLY EVIQSTLDGL LCTSLPVWLE NHTALTVVMA SKGYPGDYTK GVEITGFPEA QALGLEVFHA GTALKNGKVV THGGRVLAVT AIRENLISAL EEAKKGLAAI KFEGAIYRKD VGFRAIAFLQ QPR

    Kreuzreaktivität

    Human

    Produktmerkmale

    Antibody Reactive Against Recombinant Protein.

    Immunogen

    GART (AAH38958.1, 1 a.a. ~ 433 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    Isotyp

    IgG1
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    In 1x PBS, pH 7.4

    Handhabung

    Aliquot to avoid repeated freezing and thawing.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Baresova, Krijt, Skopova, Souckova, Kmoch, Zikanova: "CRISPR-Cas9 induced mutations along de novo purine synthesis in HeLa cells result in accumulation of individual enzyme substrates and affect purinosome formation." in: Molecular genetics and metabolism, Vol. 119, Issue 3, pp. 270-277, (2016) (PubMed).

    Genovese, Gualandi, Taddia, Marverti, Pirondi, Marraccini, Perco, Pelà, Guerrini, Amoroso, Esposito, Martello, Ponterini, DArca, Costi: "Mass spectrometric/bioinformatic identification of a protein subset that characterizes the cellular activity of anticancer peptides." in: Journal of proteome research, Vol. 13, Issue 11, pp. 5250-61, (2014) (PubMed).

    Banerjee, Ghosh, Chatterjee, Sinha, Nandagopal: "No Evidence for Mutations that Deregulate GARS-AIRS-GART Protein Levels in Children with Down Syndrome." in: Indian journal of clinical biochemistry : IJCB, Vol. 27, Issue 1, pp. 46-51, (2013) (PubMed).

    Noelker, Schwake, Balzer-Geldsetzer, Bacher, Popp, Schlegel, Eggert, Oertel, Klockgether, Dodel: "Differentially expressed gene profile in the 6-hydroxy-dopamine-induced cell culture model of Parkinson's disease." in: Neuroscience letters, Vol. 507, Issue 1, pp. 10-5, (2012) (PubMed).

    Field, Anguera, Page, Stover: "5,10-Methenyltetrahydrofolate synthetase activity is increased in tumors and modifies the efficacy of antipurine LY309887." in: Archives of biochemistry and biophysics, Vol. 481, Issue 2, pp. 145-50, (2009) (PubMed).

  • Target

    GART (Phosphoribosylglycinamide Formyltransferase (GART))

    Andere Bezeichnung

    GART

    Hintergrund

    Full Gene Name: phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
    Synonyms: AIRS,GARS,GARTF,MGC47764,PAIS,PGFT,PRGS

    Gen-ID

    2618
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