CD163 Antikörper (AA 101-200)
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- Target Alle CD163 Antikörper anzeigen
- CD163
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Bindungsspezifität
- AA 101-200
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CD163 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Human
- Homologie
- Mouse,Rat
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CD163.
- Isotyp
- IgG
- Top Product
- Discover our top product CD163 Primärantikörper
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anti-CD163 (CD163) (AA 1001-1121) antibody (FITC)
CD163 Reaktivität: Human, Maus, Ratte, Schwein, Hund WB, FACS, IF (cc), IF (p) Wirt: Kaninchen Polyclonal FITC
anti-CD163 (CD163) (AA 43-196) antibodyCD163 Reaktivität: Human IHC, ELISA, ISt, Coat, StM Wirt: Maus Monoclonal M130-2162 unconjugated
anti-CD163 (CD163) (AA 42-259) antibodyCD163 Reaktivität: Human, Maus WB, FACS, IHC, ELISA Wirt: Maus Monoclonal 7G5E2 unconjugated
anti-CD163 (CD163) (AA 43-196) antibodyCD163 Reaktivität: Human WB, IHC, ISt, StM Wirt: Maus Monoclonal M130-1210 unconjugated
anti-CD163 (CD163) (AA 697-972) antibodyCD163 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-CD163 (CD163) (AA 47-201) antibodyCD163 Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-CD163 (CD163) (AA 1092-1109), (C-Term) antibodyCD163 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-CD163 (CD163) (AA 693-939) antibodyCD163 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-CD163 (CD163) antibodyCD163 Reaktivität: Human FACS, IHC, ELISA Wirt: Kaninchen Monoclonal 7B2 unconjugated Recombinant Antibody
anti-CD163 (CD163) antibodyCD163 Reaktivität: Human WB, IHC, IF, IHC (p) Wirt: Maus Monoclonal 3C4 unconjugated
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- CD163
- Andere Bezeichnung
- CD163 (CD163 Produkte)
- Hintergrund
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Synonyms: Scavenger receptor cysteine-rich type 1 protein M130, CD163, sCD163, M130
Background: Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH -dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells. After shedding, the soluble form (sCD163) may play an anti-inflammatory role, and may be a valuable diagnostic parameter for monitoring macrophage activation in inflammatory conditions.
- Gen-ID
- 9332
- UniProt
- Q86VB7
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