RbAp46/48 Antikörper

Produktnummer ABIN5608738

Der Maus Monoklonal anti-RbAp46/48 Antikörper (Klon 6D1) (ABIN5608738) detektiert spezifisch RbAp46/48 in WB und IF (cc). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für RbAp46/48 Antikörper (ABIN5608738)

Target: RbAp46/48

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))

Klon: 6D1

Produktdetails

Kreuzreaktivität: Human

Aufreinigung: Ascites fluid from mouse containing 0.05% azide

Immunogen: Monoclonal antibody raised in mouse against the full length human RbAp48 protein (Retinoblastoma-binding protein p48) fused to GST. The antibody recognizes both RbAp48 and RbAp46

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascites fluid with 0.05 % sodium azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Antigendetails

Target: RbAp46/48

Andere Bezeichnung: RbAp 46/48

Hintergrund:

Synonyms: Histone-binding protein RBBP4, RBBP4, p48, RBBP-4, RBAP48

Background: Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair, the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression, the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling, the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development, and the NURF (nucleosome remodeling factor) complex.

Gen-ID: 5928

UniProt: Q09028