HDAC8 Antikörper (N-Term)

Produktnummer ABIN5596728

Hersteller Produkt- Nr.: 600-401-j72

Der Kaninchen Polyklonal Anti-HDAC8-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, HDAC8 in Proben von Human zu detektieren.

Kurzübersicht für HDAC8 Antikörper (N-Term) (ABIN5596728)

Target: HDAC8 (Histone Deacetylase 8 (HDAC8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-HDAC8 Antikörper

Bindungsspezifität: N-Term

Hersteller Produkt- Nr.: 600-401-j72

Hersteller: Rockland

Verwendungszweck: HDAC8 (near N-terminus) Antibody

Kreuzreaktivität (Details): A BLAST analysis was used to suggest cross-reactivity with rat, mouse, human, and bovine based on 100 % sequence homology.

Produktmerkmale: Synonyms: rabbit anti-HDAC-8 antibody, HDAC8, HDAC 8, HD-8, HD 8, Histone deacetylase 8, Histone deacetylase-8, HD8, HDACL1, CDA07

Aufreinigung: Anti-HDAC8 was affinity purified from monospecific antiserum by immunoaffinity chromatography.

Sterilität: Sterile filtered

Immunogen:

Immunogen: Anti-HDAC8 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide near the N-terminus of human HDAC8 protein.

Immunogen Type: Conjugated Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Application Note: Anti-HDAC8 antibody has been tested by ELISA, and western blot and is useful for Immunohistochemistry. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~41 kDa corresponding to the appropriate cell lysate or extract.

Western Blot Dilution: 1 μg/mL

ELISA Dilution: 1: 10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 30 % Glycerol

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu HDAC8

Target: HDAC8 (Histone Deacetylase 8 (HDAC8))

Andere Bezeichnung: HDAC8

Hintergrund: Background: HDAC8 is located in the nucleus and cytoplasm, expressed weakly in most tissues with higher expression in the heart, brain, kidney, pancreas, liver, lunch, placenta, prostate, and kidney. It is responsible for the deacetylation of lysine residues on the N-terminal region of the core histones (H2A, H2B, H3 and H4). The result of deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Anti-HDAC8 therefore is ideal for investigators interested in Stem Cells , Cardiovascular , or Epigenetics and Nuclear Signaling research.

UniProt: Q9BY41

Pathways: Cellular Glucan Metabolic Process