Rekombinanter TNFSF4 (Oxelumab Biosimilar) Antikörper
Kurzübersicht für Rekombinanter TNFSF4 (Oxelumab Biosimilar) Antikörper (ABIN5564244)
Target
Antikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- anti-OX40L (human), mAb (rec.) (blocking) (R4930) (preservative free)
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Spezifität
- Recognizes human OX40L.
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Produktmerkmale
- Recombinant Antibody. Recognizes human OX40L. Species cross-reactivity: Human. Clone: R4930. Isotype: Human IgG1kappa. Applications: FACS, FUNC, FUNC (Blocking). Host: CHO cells. Liquid. In PBS. OX40L is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as costimulator through interaction with its ligand OX40 on T cells, stimulating T cell activation, proliferation and cytokine production. OX40L is expressed on antigen presenting cells including B cells, dendritic cells, mast cells and endothelium.
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Reinheit
- >95 % (SDS-PAGE)
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Endotoxin-Niveau
- <0.001EU/μg
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Immunogen
- Recombinant human OX40L.
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Isotyp
- IgG1 kappa
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Kommentare
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This antibody is a biosimilar generically called Oxelumab (CAS 1186098-83-8) and originally developed by Genentech. Oxelumab is a OX40 ligand blocker designed for the prevention of allergen-induced airway inflammation in adults with mild asthma. Potentially other application areas are transplantation and autoimmunity research or protection against inflammation-driven fibrosis.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- In PBS.
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Konservierungsmittel
- Without preservative
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Handhabung
- Avoid freeze/thaw cycles.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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+4°C
-20°C
Stable for at least 1 year after receipt when stored at -20°C. Stable for at least 3 months after receipt when stored at +4°C.
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Haltbarkeit
- 12 months
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- TNFSF4 (Oxelumab Biosimilar)
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Substanzklasse
- Biosimilar
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Hintergrund
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Alternate Names/Synonyms: CD252, CD134L, OX40 Ligand, TNFSF4, Tumor Necrosis Factor Superfamily Member 4, TAX Transcriptionally-activated Glycoprotein 1, TXGP1, gp34
Product Description: OX40L [CD252, CD134L] is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as costimulator through interaction with its ligand OX40 on T cells, stimulating T cell activation, proliferation and cytokine production. OX40L is expressed on antigen presenting cells including B cells, dendritic cells, mast cells and endothelium.
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UniProt
- P23510
Target
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