SFMBT1 Antikörper (C-Term)

Produktnummer ABIN5563984

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-SFMBT1 Antikörper (ABIN5563984) detektiert spezifisch SFMBT1 in WB, IP, ChIP, IF und ChIP-seq. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für SFMBT1 Antikörper (C-Term) (ABIN5563984)

Target: SFMBT1 (Scm-Like with Four Mbt Domains 1 (SFMBT1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SFMBT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), Immunofluorescence (IF), ChIP DNA-Sequencing (ChIP-seq)

Produktdetails anti-SFMBT1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: SFMBT1 antibody (pAb)

Spezifität: Mouse

Aufreinigung: Affinity Purified

Immunogen: This antibody was raised against a peptide within the C-terminal region of mouse SFMBT1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500 - 1:2,500 dilution

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Referenzen für anti-SFMBT1 Antikörper (ABIN5563984)

Zhang, Bonasio, Strino, Kluger, Holloway, Modzelewski, Cohen, Reinberg: "SFMBT1 functions with LSD1 to regulate expression of canonical histone genes and chromatin-related factors." in: Genes & development, Vol. 27, Issue 7, pp. 749-66, (2013) (PubMed).

Details zu SFMBT1

Target: SFMBT1 (Scm-Like with Four Mbt Domains 1 (SFMBT1))

Andere Bezeichnung: SFMBT1

Hintergrund: SFMBT1 (Scm-Like With Four Mbt Domains 1) is a histone-binding protein, which is part of various corepressor complexes. Mediates the recruitment of corepressor complexes to target genes, followed by chromatin compaction and repression of transcription. Plays a role during myogenesis: required for the maintenance of undifferentiated states of myogenic progenitor cells via interaction with MYOD1. Interaction with MYOD1 leads to the recruitment of associated corepressors and silencing of MYOD1 target genes. Part of the SLC complex in germ cells, where it may play a role during spermatogenesis.

Molekulargewicht: 110 kDa

NCBI Accession: NP_062333