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HDAC4 Antikörper

HDAC4 Reaktivität: Human, Maus, Ratte WB, IF (cc) Wirt: Kaninchen Monoclonal 6B10 unconjugated
Produktnummer ABIN5557481
  • Target Alle HDAC4 Antikörper anzeigen
    HDAC4 (Histone Deacetylase 4 (HDAC4))
    Reaktivität
    • 116
    • 47
    • 33
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 104
    • 13
    • 1
    Kaninchen
    Klonalität
    • 105
    • 13
    Monoklonal
    Konjugat
    • 67
    • 8
    • 7
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HDAC4 Antikörper ist unkonjugiert
    Applikation
    • 78
    • 47
    • 24
    • 24
    • 15
    • 13
    • 11
    • 11
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))
    Aufreinigung
    Purified by Protein A.
    Immunogen
    Recombinant human HDAC4 protein, around C-terminal 100aa.
    Klon
    6B10
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    WB 1:1000-2000
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C
    Haltbarkeit
    12 months
  • Target
    HDAC4 (Histone Deacetylase 4 (HDAC4))
    Andere Bezeichnung
    HDAC4 (HDAC4 Produkte)
    Hintergrund

    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008].

    Synonyms: HDAC4Ser246, HDAC4S246, p-HDAC4Ser246, p-HDAC4S246, HD 4, HD4, HDAC 4, HDAC A, HDACA, Histone Deacetylase 4, Histone Deacetylase A, KIAA0288, EC 3.5.1.98, HA6116, HDA4_CAEEL, Histone deacetylase 4, CeHDA-7, Histone deacetylase 7.

    Gen-ID
    9759
    UniProt
    P56524
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
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