Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

ARF1 Antikörper

ARF1 Reaktivität: Human, Ratte, Maus WB, IF (cc) Wirt: Kaninchen Monoclonal 1D4 unconjugated
Produktnummer ABIN5557419
  • Target Alle ARF1 Antikörper anzeigen
    ARF1 (ADP-Ribosylation Factor 1 (ARF1))
    Reaktivität
    • 62
    • 40
    • 28
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 64
    • 13
    • 1
    Kaninchen
    Klonalität
    • 57
    • 21
    Monoklonal
    Konjugat
    • 34
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ARF1 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 31
    • 22
    • 15
    • 13
    • 13
    • 10
    • 8
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))
    Aufreinigung
    Purified by Protein A.
    Immunogen
    Recombinant human ARF1 protein, full length.
    Klon
    1D4
    Isotyp
    IgG
    Top Product
    Discover our top product ARF1 Primärantikörper
  • Applikationshinweise
    WB 1:1000-2000
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C
    Haltbarkeit
    12 months
  • Target
    ARF1 (ADP-Ribosylation Factor 1 (ARF1))
    Andere Bezeichnung
    ARF1 (ARF1 Produkte)
    Hintergrund

    GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity, the function is linked to AMPA receptor (AMPAR) trafficking, regulation of synaptic plasicity of excitatory synapses and spine shrinkage during long-term depression (LTD).

    Synonyms: ADP-ribosylation factor 1, ARF1

    Gen-ID
    375
    UniProt
    P84077
    Pathways
    Transition Metal Ion Homeostasis, Inositol Metabolic Process
Sie sind hier:
Kundenservice