CBR1 Antikörper (AA 201-277)

Produktnummer ABIN5557348

Produktdetails anti-CBR1 Antikörper

Target: CBR1 (Carbonyl Reductase 1 (CBR1))

Bindungsspezifität: AA 201-277

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus

Homologie: Human,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CBR1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu CBR1

Target: CBR1 (Carbonyl Reductase 1 (CBR1))

Andere Bezeichnung: CBR1 (CBR1 Produkte)

Synonyme: LOC100222525 antikoerper, MGC131152 antikoerper, CBR antikoerper, SDR21C1 antikoerper, hCBR1 antikoerper, 9-KPR antikoerper, AW261796 antikoerper, CR antikoerper, Cbr antikoerper, carbonyl reductase 1 antikoerper, carbonyl reductase [NADPH] 1 antikoerper, carbonyl reductase 1 S homeolog antikoerper, carbonyl reductase antikoerper, cbr1 antikoerper, CBR1 antikoerper, LOC100222525 antikoerper, cbr1.S antikoerper, Smp_033530.3 antikoerper, LOC610164 antikoerper, Cbr1 antikoerper

Hintergrund:

Synonyms: Carbonyl reductase [NADPH] 1, CBR1, 15-hydroxyprostaglandin dehydrogenase [NADP(+)], NADPH-dependent carbonyl reductase 1, Prostaglandin 9-ketoreductase, Prostaglandin-E(2) 9-reductase (EC:1.1.1.189), Short chain dehydrogenase/reductase family 21C member 1, CBR, CRN, SDR21C1

Background: NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.

Gen-ID: 873

UniProt: P16152