ALAS1 Antikörper

Produktnummer ABIN5557346

Dieses Anti-ALAS1-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von ALAS1 in WB und IF (cc). Geeignet für Human und Maus.

Kurzübersicht für ALAS1 Antikörper (ABIN5557346)

Target: ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ALAS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))

Klon: 1G11

Produktdetails anti-ALAS1 Antikörper

Kreuzreaktivität: Human, Maus

Aufreinigung: Purified by Protein A.

Immunogen: Recombinant human Alas1 protein, around C-terminal 200aa.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu ALAS1

Target: ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

Andere Bezeichnung: Alas1

Hintergrund:

Synonyms: 5-aminolevulinate synthase, nonspecific, mitochondrial, ALAS1, 5-aminolevulinic acid synthase 1, Delta-ALA synthase 1, Delta-aminolevulinate synthase 1, ALAS1, ALAS3, ALASH, OK/SW-cl.121

Background: This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme, a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]

Gen-ID: 211

UniProt: P13196

Pathways: Regulation of Lipid Metabolism by PPARalpha