Rekombinanter ALAS1 Antikörper (C-Term)
Kurzübersicht für Rekombinanter ALAS1 Antikörper (C-Term) (ABIN5557346)
Target
Alle ALAS1 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- Alas1 (1G11) Recombinant Antibody
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Kreuzreaktivität
- Human
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Aufreinigung
- Purified by Protein A.
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Immunogen
- Recombinant human Alas1 protein, around C-terminal 200aa.
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Isotyp
- IgG
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Applikationshinweise
- WB(1:300-5000)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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- ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))
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Andere Bezeichnung
- Alas1
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Hintergrund
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Synonyms: 5-aminolevulinate synthase, nonspecific, mitochondrial, ALAS1, 5-aminolevulinic acid synthase 1, Delta-ALA synthase 1, Delta-aminolevulinate synthase 1, ALAS1, ALAS3, ALASH, OK/SW-cl.121
Background: This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme, a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
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Gen-ID
- 211
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UniProt
- P13196
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Pathways
- Regulation of Lipid Metabolism by PPARalpha
Target
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